Basic Information

Product Name: Epoxiconazole

Chemical Category: Triazole Fungicide (DMI – Demethylation Inhibitor)

Molecular Formula: C₁₇H₁₃ClFN₃O

Molecular Weight: 329.76 g/mol

CAS No.: 135319-73-2

Appearance: White or off-white crystalline solid

Mode of Action

Epoxiconazole is a systemic triazole fungicide that inhibits ergosterol biosynthesis in fungal cell membranes. By blocking sterol demethylation, it disrupts fungal cell growth and reproduction, providing effective control of a wide range of plant pathogenic fungi.

Main Applications

Epoxiconazole is a broad-spectrum fungicide widely used in cereal crops and cash crops:

• Cereals (wheat, barley, oats): Control of rusts, Septoria leaf blotch, leaf spots, powdery mildew, Fusarium head blight.

• Banana, Coffee, and other crops: Control of leaf spots, rusts, and other fungal diseases.

Product Formulations

• Suspension Concentrate (SC): 125 g/L, 250 g/L, 500 g/L

• Water Dispersible Granule (WDG)

• Emulsifiable Concentrate (EC)

Application method: Foliar spray. Best results are achieved when applied preventively or at the early stage of disease development.

Environmental Impact

Mammalian Toxicity: Low to moderate toxicity (Oral LD50 in rats approx. 3160 mg/kg).

Ecotoxicology: Highly toxic to aquatic organisms; potential long-term environmental risks.

Safety Measures: Operators should wear protective gloves, goggles, and clothing. Avoid contact with skin, eyes, and contamination of water bodies.

Regulatory Status

European Union: Approval withdrawn due to health and environmental concerns.

Australia / New Zealand: Registered for use in cereals and other crops.

United States: Not registered for domestic use; import tolerances established for crops such as banana and coffee.

Precautions

Avoid repeated or sole use to reduce resistance risk; rotate or tank-mix with fungicides of different modes of action.

Observe pre-harvest intervals to ensure compliance with MRL standards.

Prevent spray drift and contamination of rivers, lakes, and aquatic habitats.